Pregnancy: Any medication women who are pregnant ingest will affect the fetus.
● Most medications are potentially harmful to the fetus. Therefore, prescribers must weigh the benefits of maternal medication administration against possible fetal risk.
● Medications women take during pregnancy include nutritional supplements (iron, vitamins, minerals) and medications that treat nausea, vomiting, gastric acidity, and mild discomforts. The U.S. Food and Drug Administration classifies medications in five categories that range from remote risk to proven risk of fetal harm.
● Due to the physiologic changes during pregnancy in the kidney, liver, and gastrointestinal tract, women might require a compensatory increase or decrease in medication dosage, depending on the specific medication.
● Providers manage chronic medical disorders such as diabetes mellitus and hypertension in conjunction with careful maternal‑fetal monitoring. Pregnancy is a contraindication for live-virus vaccines (measles, mumps, polio, rubella, varicella, yellow fever) due to possible teratogenic effects, including gross malformations and neurobehavioral, congenital, and metabolic anomalies. The Advisory Committee on Immunization Practices recommends that women who are pregnant during influenza season receive the inactivated influenza vaccine.
Lactation: Most medications women who are lactating take enter breast milk. These women should avoid medications that have an extended half‑life, are sustained-released, or are harmful to infants. For medications that are safe, give the medication immediately after breastfeeding to minimize the medication’s concentration in the next feeding. Give the lowest effective dosage for the shortest possible time.
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